Thursday, March 13, 2014

Women The Males In Your Family Over 50 Must Have This list of Vitamins & Nutrients In Their Diets To Stop Prostate Cancer


Barron’s Medical Journal Reporting from University of Miami Miami, Fl USA

Women The Males In Your Family Over 50 Must Have This list of Vitamins & Nutrients In Their Diets To Stop Prostate Cancer


Miami Florida (AP)---- Barron’s Medical Journal asks how many people have someone in their family that has prostate cancer. The result of our survey says ----- 1 in 4 people has a relative or friends that have experiences prostate cancer. With genomics now solving all kinds of medical issues, we found a PCA3 , also (referred to as DD3) gene prostate cancer antigen 3 that gives Doctors clues on how better to advises us on living longer with prostate cancer, Gene PCA3 is a gene that expresses a non-coding RNA. PCA3 is only expressed in human prostate tissue, and the gene is highly overexpressed in prostate cancer. Because of its restricted expression profile, the PCA3 RNA is useful as a tumor marker.

If you make sure the males in your family over fifty years old have, this list of vitamins & nutrients in their diets you can stop prostate cancer from growing and extend their life. ---- Vitamin D,-- antioxidant,-- antiviral,-- antibacterial,-- antifungal,-- anticarcinogenic,-- antimutagenic -- anti-inflammatory properties.-- Protein, -- dietary fiber,-- niacin, --Vitamin C,-- Vitamin E,-- Vitamin K, --sodium,-- potassium, --calcium, --copper,-- iron, magnesium and zinc.----

The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study demonstrated a 32% reduction in prostate cancer incidence in response to daily α-tocopherol supplementation. We examined baseline serum concentrations of α-tocopherol and γ-tocopherol to compare their respective associations with prostate cancer risk. From the ATBC Study cohort of 29 133 Finnish men, 50–69 years old, we randomly selected 100 incident prostate cancer case patients and matched 200 control subjects. Odds ratios and 95% confidence intervals (CIs) were estimated for the serum tocopherols (measured by high-performance liquid chromatography) using logistic regression models. All P values were two-sided. Odds ratios for the highest versus the lowest tertiles were 0.49 (95% CI = 0.24 to 1.01, Ptrend = .05) for α-tocopherol and 0.57 (95% CI = 0.31 to 1.06, Ptrend = .08) for γ-tocopherol. Further analyses indicated that the association of high serum tocopherols with low prostate cancer risk was stronger in the α-tocopherol–supplemented group than in those not receiving α-tocopherol. Participants with higher circulating concentrations of the major vitamin E fractions, α-tocopherol and γ-tocopherol, had similarly lower prostate cancer risk.

Vitamin E occurs naturally as four tocopherols and four tocotrienols. γ-Tocopherol, the most prevalent form of Brought To You By Norton Ditto vitamin E in the typical U.S. diet(1–3), has received increasing attention recently (2). α-Tocopherol is the predominant form of vitamin E in plasma, regardless of dietary intake, due to preferential binding by the hepatic α-tocopherol transfer protein (1–3).

α-Tocopherol supplementation reduced prostate cancer incidence by 32% (95% confidence interval [CI] = −47% to −12%) in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study (4). Observational data regarding serum α-tocopherol and prostate cancer risk have been mixed, however (5–15), and few studies measured γ-tocopherol (7–11). We therefore conducted a nested case–control study within the ATBC Study cohort to compare the prostate cancer risk associations of serum α-tocopherol and γ-tocopherol.


· Vitamin D helps the body use calcium and phosphorus to make strong bones and teeth. It is obtained primarily through exposure of the skin to sunlight, but it can also be obtained from some foods and dietary supplements.


· Many studies in humans, but not all, suggest that higher intakes of vitamin D or higher levels of vitamin D in the blood are associated with a reduced risk of colorectal cancer.


· Whether vitamin D is associated with reduced risks of other cancers, including breast, prostate, and pancreatic cancers, remains unclear.


· The National Cancer Institute (NCI) does not recommend for or against the use of vitamin D supplements to reduce the risk of colorectal or any other type of cancer


Vitamin D is the name given to a group of fat-soluble prohormones (substances that usually have little hormonal activity by themselves but that the body can turn into hormones). Vitamin D helps the body use calcium and phosphorus to make strong bones and teeth. Skin exposed to sunshine can make vitamin D, and vitamin D can also be obtained from certain foods. Vitamin Ddeficiency can cause a weakening of the bones that is called rickets in children and osteomalaciain adults.


Two major forms of vitamin D that are important to humans are vitamin D2, or ergocalciferol, and vitamin D3, or cholecalciferol. Vitamin D2 is made naturally by plants, and vitamin D3 is made naturally by the body when skin is exposed to ultraviolet radiation in sunlight. Both forms are converted to 25-hydroxyvitamin D in the liver. 25-Hydroxyvitamin D then travels through the blood to the kidneys, where it is further modified to 1,25-dihydroxyvitamin D, or calcitriol, the active form of vitamin D in the body. The most accurate method of evaluating a person’s vitamin D status is to measure the level of 25-hydroxyvitamin D in the blood.


Most people get at least some of the vitamin D they need through sunlight exposure. Dietary sources include a few foods that naturally contain vitamin D, such as fatty fish, fish liver oil, and eggs. However, most dietary vitamin D comes from foods fortified with vitamin D, such as milk, juices, and breakfast cereals. Vitamin D can also be obtained through dietary supplements.


The Institute of Medicine (IOM) of the National Academies has developed the following recommended daily intakes of vitamin D, assuming minimal sun exposure (1,2):


· For those between 1 and 70 years of age, including women who are pregnant or lactating, the recommended dietary allowance (RDA) is 15 micrograms (μg) per day. Because 1 μg is equal to 40 International Units (IU), this RDA can also be expressed as 600 IU per day.

· For those 71 years or older, the RDA is 20 μg per day (800 IU per day). For infants, the IOM could not determine an RDA due to a lack of data. However, the IOM set an Adequate Intake level of 10 μg per day (400 IU per day), which should provide sufficient vitamin D.

Although the average dietary intakes of vitamin D in the United States are below guideline levels, data from the National Health and Nutrition Examination Survey revealed that more than 80 percent of Americans had adequate vitamin D levels in their blood.

Even though most people are unlikely to have high vitamin D intakes, it is important to remember that excessive intake of any nutrient, including vitamin D, can cause toxic effects. Too much vitamin D can be harmful because it increases calcium levels, which can lead to calcinosis (the deposit of calcium salts in soft tissues, such as the kidneys, heart, or lungs) and hypercalcemia(high blood levels of calcium). The safe upper intake level of vitamin D for adults and children older than 8 years of age is 100 μg per day (4000 IU per day). Toxicity from too much vitamin D is more likely to occur from high intakes of dietary supplements than from high intakes of foods that contain vitamin D. Excessive sun exposure does not cause vitamin D toxicity. However, the IOM states that people should not try to increase vitamin D production by increasing their exposure to sunlight because this will also increase their risk of skin cancer.

Early epidemiologic research showed that incidence and death rates for certain cancers were lower among individuals living in southern latitudes, where levels of sunlight exposure are relatively high, than among those living at northern latitudes. Because exposure to ultraviolet light from sunlight leads to the production of vitamin D, researchers hypothesized that variation in vitamin D levels might account for this association. However, additional research based on stronger study designs is required to determine whether higher vitamin D levels are related to lower cancer incidence or death rates.

Experimental evidence has also suggested a possible association between vitamin D and cancer risk. In studies of cancer cells and of tumors in mice, vitamin D has been found to have several activities that might slow or prevent the development of cancer, including promoting cellular differentiation, decreasing cancer cell growth, stimulating cell death (apoptosis), and reducing tumor blood vessel formation (angiogenesis)

Milk thistle (Silybum marianum) has been used for 2,000 years as an herbal remedy for a variety of ailments, particularly liver, kidney, and gall bladder problems. Several scientific studies suggest that substances in milk thistle (especially a flavonoid called silymarin) protect the liver from toxins, including certain drugs such as acetaminophen (Tylenol), which can cause liver damage in high doses. Silymarin has antioxidant and anti-inflammatory properties, and it may help the liver repair itself by growing new cells