Scientist Can Rebuild Your Brain:

Robert-Barron Graham Reporting From University Of Texas Medical Center In The Texas Medical Center Houston, Texas USA Scientist Can Rebuild Your Brain:: Houston ( AP )--- Genomics and Bioinformatics has introduced The Next generation of Human Science technology to make our lives better when we get sick. One area of major concern has been for years, how do we help those patients who has lost their memories? The implant has been developed at the University of Southern California and Wake Forest Baptist Medical Centre in Winston-Salem, North Carolina, in a decade-long collaboration.

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The Team has created A prosthetic implant, which is made up of many tiny electrodes that are implanted into the brain, utilizes a computer algorithm that mimics that electrical signaling process that the brain uses to consolidate short-term memories into permanent ones. Apart from expressing sheer wonder at the speed of in bioelectronics, how should society respond? Using information technology to manipulate human thoughts and memories clearly raises moral and ethical issues, but first we should welcome the promised medical benefits. If clinical trials confirm that the USC prosthesis can restore memory in relatively young patients with head injuries or stroke, by encoding their brain signals to bypass the damaged brain region, that would be a fantastic advance.

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But the researchers have also mentioned Alzheimer’s disease as a possible long-term application of the technology. Restoring memory through an implant in Alzheimer’s patients, who suffer from widespread and diffuse neurodegeneration, is likely to be more difficult technically than rerouting neural signals past a localised lesion caused by head injury or stroke.

Brought To You By Fashion Woodlands Even if this becomes possible, there are troubling questions about the resources that should be devoted to using neural implants to treat progressive diseases in the elderly — and more generally about who should receive bioelectronic therapy.

NIH is making it more and more possible for scientist to collaborate on brain implants. The NIH BRAIN Initiative has released three funding opportunity announcements for partnerships between clinical investigators and manufacturers of the latest-generation implantable stimulating and/or recording devices for clinical neuroscience research in humans.

A central focus of the BRAIN Initiative is development of technologies for recording and modulating neural circuits. Such technologies may be incorporated into devices to be implanted in the brain or spinal cord that can, for example, treat Parkinson’s disease or restore movement in the case of spinal cord injury. NIH has released three funding opportunity announcements (FOAs) for Fiscal Year 2016 to fund research partnerships between clinical investigators and manufacturers of latest-generation implantable stimulating and/or recording devices to conduct clinical research in the central nervous system (CNS). Development of implantable CNS devices for market-approved therapeutics can take many years and cost tens or even hundreds of millions of dollars, with much of the cost coming from stringent regulatory requirements for manufacturing and safety testing. The goal of the partnerships is to leverage the existing safety and regulatory data that is already available for manufacturers’ latest-generation devices, thereby reducing the time and cost for clinical researchers to explore new or improved therapies for neuropsychiatric disorders.

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Two years we reported President Obama has stated in his State Of Union Address. It Is important for the science community to increase their Research on Brain Activity Mapping And Genomics. In the long run we can reduce Heath care cost by being able to determine which patents will have a neurological disorders.

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A map of the brain connections would be helpful for interpreting measurements of the signals transmitted between neurons. In the human brain, these signals travel in a complex network of 100 billion or so neurons, each of which is connected to 10,000 others.

The function of neural circuits is an emergent property arising from the coordinated activity of large numbers of neurons. To capture this, we propose launching a large-scale, international public effort, the Brain Activity Map Project, aimed at reconstructing the full record of neural activity across complete neural circuits.

In 1953 James Watson and Francis Crick proposed the double helix structure for DNA. The double helix consists of a long chain of repeated units called nucleotides, of which there are four types: A, C, G, and T. Hereditary information is written in DNA using this alphabet of four letters. In the human genome, the sequence of nucleotides is about one billion letters long. The reading of this sequence was finally completed by the Human Genome Project in 2003.

Barrons Medical Journal spoke with Francis Collins The CEO of The National Institutes of Health. Collins said that, the scientists at NIH and private foundations like the Howard Hughes Medical Institute in Chevy Chase, Md., and the Allen Institute for Brain Science in Seattle will all be participating in the project .

Brought To You By Fashion Woodlands First, connectomics will help reveal how the brain stores and retrieves information about the past. Neuroscientists believe that memories are stored in the connections between neurons. According to this theory, connections change when a new memory is stored. That such changes can happen is not in doubt. Neuroscientists have found that new synapses can be created and that the strengths of existing synapses can be altered. What remains uncertain is whether these changes are indeed the basis of memory.

We can safely report President Obama in his tenure has exponentially extended our quality of life.

Houston Is The Rome Of Fashion & Vivian Wise Is The Aurelia Cotta - The Queen Of Fashion:

Barron’s Medical Journal Bobby Graham Reporting from the Houston Galleria, Houston TX USA

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Houston Is The Rome Of Fashion And Vivian Wise Is The Aurelia Cotta & The Queen Of Fashion:

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Houston ( AP ) -- Houston is the Idea Market for designers from all over the world, The reason for this-- There is No State Employment Taxes, Unemployment is at a all-time low and with Exxon, Shell, BP, and Chevron oil companies having a huge presence in Houston, makes Houston the "Rome of Fashion".

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Vivian understands Adam Smith Economic Theory of The Fashion World, first who is Adam Smith? Adam said “Capitalism is a system of largely private ownership that is open to new ideas, new firms and new owners—in short, to new capital. Capitalism’s rationale to proponents and critics alike has long been recognized to be its dynamism, that is, its innovations and, more subtly, its selectiveness in the innovations it tries out.” Thus giving Houston The New River Oaks District.

Wise understand that the economic and social institutions engender innovation in the more capitalist of today’s advanced economies, and what institutions function badly in this regard? How large are the benefits of this fashion system both in productivity and more broadly in the rewards to its participants? How much worse (if at all) is this system with respect to stability and inclusion - compared with corporatist fashion systems found in continental Western Europe and East Asia? What changes or additions to those institutions and policies could be developed to improve its dynamism, stability or inclusiveness In the fashion world is why Wise is putting on a glamours Fashion production ?

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As The season change in several part of the world, one thing is so amazing about Houston, TX USA is season seem to be in two parts. Starting the 1st of September, Fashion is in full gear starting with The Cadillac Fashion Show, put on by Simons Malls also known as The Houston Galleria.

This Year, 2015 Hosted by Vogue Magazine gave this year’s show the creditability needed to be a High Valued Fashion Show.

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Now to take Houston to the next level in the global fashion world is Vivian Wise. Vivian is going to Have her 1st show under her Brand. “Heart of Fashion “ A three-night event in The Heart of downtown Houston. This Event ha has caught the ‘eye of (The Global Fashion World)

Vivian Wise revealed that she and founder Jared Lang have parted ways and that she is planning a new series of runway shows showcasing the Houston fashion scene in November under a new name and at a new location. Legendary model Carmen Dell'Orefice will be honored with the first Legacy Award and Wise plans to honor a Houston charity each night.

In the wider luxury goods, stellar growth appears be in high demand. After a five-years of soaring revenues and profits, triggered by Asian, Mexican consumers enthusiasm and volatile exchange rates that have increased manufacturing and spread fashion sales regions in the Gulf Coast Region.

“The new growth frontier,” Luca Solca, an Exane BNP Paribas analyst, say brands’ focus on High End Women's-Wear growth in Houston has produce the greatest market for fashion designers and Vivian will be show Casing the product of a Market equilibrium Supply and Demand that has every major fashion writer designers and manufactures looking forward this year’s Vivian Wise Fashion show, also know as Heart of Fashion

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We Are The Smartest Human Beings Ever: Who is 2nd Octopus

Barron’s Medical Journal Robert Graham Reporting from Rice University Bioscience Center Located in the Texas Medical Center in Houston, TX USA

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We Are The Smartest Human Beings Ever: Who is 2nd Octopus

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Houston, TX ( AP ) -- We Are The Smartest Human Being Ever. Barron’s Medical Journal has discovered we have a wonderful amount of intelligence going for us in 2015. One of the most significant sciences finding in the last twenty years is the study of Genetics and Genomics. Let’s start by providing a understanding of Genetics. Genetics is the branch of science concerned with genes, heredity, and variation in living organisms. It seeks to understand the process of trait inheritance from parents to offspring, including the molecular structure and function of genes, gene behavior in the context of a cell or organism. Genomics is the study of the full genetic complement of an organism (the genome). It employs recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyse the structure and function of genomes. The Breaking new in the science communities is, the octopus genome offers clues to how the creatures evolved intelligence to rival the craftiest vertebrates.

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A octopus genome turned out to be almost as large as a human’s and to contain a greater number of protein-coding genes — some 33,000, compared with fewer than 25,000 in Homo sapiens. The octopus seems almost like an alien species. It’s spineless. It has 3 hearts. It has 8 arms lined with suckers. It can change color, texture, and shape to camouflage itself. It can climb walls and open jars. And its nervous system contains nearly half a billion neurons, more than 6 times the number in a mouse brain.

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This excess results mostly from the expansion of a few specific gene families, Ragsdale says. One of the most remarkable gene groups is the protocadherins, which regulate the development of neurons and the short-range interactions between them. The octopus has 168 of these genes — more than twice as many as mammals. This resonates with the creature’s unusually large brain and the organ’s even-stranger anatomy. Of the octopus's half a billion neurons — six times the number in a mouse — two-thirds spill out from its head through its arms, without the involvement of long-range fibres such as those in vertebrate spinal cords. The independent computing power of the arms, which can execute cognitive tasks even when dismembered, have made octopuses an object of study for neurobiologists such as Hochner and for roboticists who are collaborating on the development of soft, flexible robots.

The researchers found that the genome of the common California two-spot octopus was almost as large as a human’s genome (2.7 billion base pairs compared to 3 billion base pairs, respectively). But they estimated that it contains over 33,000 protein-coding genes—considerably more than the approximately 20,500 found in humans.

The octopus is a member of the cephalopod class, a group that includes squid and cuttlefish. The scientists found that the octopus has hundreds of genes present in cephalopods that haven’t been detected in other animals. Many of these genes are highly expressed (turned on) in specialized structures, such as the skin, the suckers, and the nervous system. For example, they found 6 genes for reflectins, which play a role in rapid, reversible changes in iridescence. Brought To You By Palm Steak House Houston

The team found a greatly expanded number of genes in 2 specific groups, or families, which were previously thought to only be enlarged in vertebrates. They noted 168 protocadherin genes, more than twice as many as humans. These genes regulate nervous system development and organization. The researchers also found nearly 1,800 genes from a group known as zinc-finger transcription factors. This is one ofthe largest groups of genes discovered to date in any animal. These genes, which code for proteins that regulate the activities of other genes, are mainly expressed in embryonic and nervous tissues, and are thought to play a role in brain development.

Nearly half of the octopus genome is composed of elements known as transposons—small pieces of DNA that can move from one location in the genome to another. They originally were referred to as “jumping genes.” A notable feature of the octopus genome is that it seems to have expanded largely through transposons moving around and reorganizing the genome.

A gene family that is involved in development, the zinc-finger transcription factors, is also highly expanded in octopuses. At around 1,800 genes, it is the second-largest gene family to be discovered in an animal, after the elephant’s 2,000 olfactory-receptor genes. The team estimates the O. bimaculoides genome is 2.7 billion base-pairs in size, with numerous long stretches of repeated sequences. They identified more than 33,000 protein-coding genes, placing the octopus genome at slightly smaller in size, but with more genes, than a human genome. The large size of the octopus genome was initially attributed to whole genome duplication events during evolution, which can lead to increased genomic diversity and complexity. This phenomenon has occurred twice in ancestral vertebrates, for example. However, Ragsdale and his colleagues found no evidence of duplication's.

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Instead, the evolution of the octopus genome was likely driven by the expansion of a few specific gene families, widespread genome shuffling and the appearance of novel genes.

The most notable expansion was in the protocadherins, a family of genes that regulate neuronal development and short-range interactions between neurons. The octopus genome contains 168 protocadherin genes - 10 times more than other invertebrates and more than twice as many as mammals. It was previously thought that only vertebrates possessed numerous and diverse protocadherin genes. The research team hypothesized that because cephalopod neurons lack myelin and function poorly over long distances, protocadherins were central to the evolution of a nervous system whose complexity depends on short-range interactions. The CephSeq Consortium and chair of its steering committee acknowledged that cephalopod researchers are at square one when it comes to this kind of genetic analysis, but the project will build momentum. “Once there’s a good assembly of one of the genomes, then the others will be much easier,” he said.

Ragsdale and Carrie Albertin, a PhD candidate in his lab, are working specifically on the genome forOctopus bimaculoides, a small, brown octopus found in the Pacific off the coast of California and Mexico. Their contribution to the project will be sequencing and assembling transcriptomes for the octopus, which will yield a complete set of mRNA, or the protein coding genes, expressed in target tissues. Albertin has isolated 19 different tissues from various embryonic stages, brain tissue and glands of the octopus, which will then be sequenced at the University of Chicago Genomics Facility, a shared, high-performance computing center on campus

Is Annise Danette Parker The Most Successful Mayor In Houston’s History:

Is Annise Danette Parker The Most Successful Mayor In Houston’s History:

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Barron’s Medical Journal reporting from the Shell office towers in Houston, Texas USA:

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Houston TX ( AP ) In a city where a Gay Woman Annise Danette Parker is looking like she is going to be the most success Mayor in the City of Houston History says Bobby Graham of Hybrid Media. The question is can the city thriving Oil and Gas Industry make the necessary changes to extend the growth and prosperity Houston is experiencing over the ten to 12 years?

The Answer is yes, because science has given the Oil and Gas Industry the same tool, that The President Obama Admiration recognizes as this country’s future Genomics Science. A great example of this is The federal government has given Royal Dutch Shell the final permit it needs to drill for oil in the Arctic Ocean off Alaska's northwest coast for the first time in more than two decades.

Brought To You By kuhl-linscomb The Bureau of Safety and Environmental Enforcement said Monday that exploratory drilling can go ahead after the oil giant brought in a required piece of equipment to stop a possible well blowout in the Chukchi Sea.

The agency in July gave Shell permission to drill only the top sections of two wells because key safety equipment hadn't arrived. You Can Find True And Real Fashion Here:

Years back Th Obama Administration ask Congress for funding to map the human brain. B.A.M Brain Activity Mapping will do for Neuroscience what the Human Genome Project has done for genetics. For every dollar The Federal Government has invested in the Human Genome Project, The American People has received a return on investment of Two Hundred and Forty Dollars.

Our brain is vast on a cosmic scale. Billions upon billions of neurons communicate with one another via trillions of connections, giving rise to what amounts to a network of networks. Widely adopted (but by no means universally accepted) theories posit that these neural networks are the wellsprings of such complex processes as perception and action. Neuro Scientists believe that a detailed BAM Brain Activity Mapping reveals valuable information about these and other cognitive functions, and perhaps human consciousness.

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The Obama Administration has sought in planning a ten-year, multi-billion dollar project. Everything that we are, our whole mental world, amounts to nothing more than neural circuits firing [in patterns] throughout the brain. By mapping circuit activity, researchers can "discover patterns that are the physical representation and origin of mental states — of thoughts, for example, or memories."

There are one million gigabytes in a petabyte. The Large Hadron Collider in Geneva generates about 10 petabytes of data annually. If the brain contains between 85 and 100 billion neurons, that means that the complete brain generates about 300,000 petabytes of data each year.

The director of the Bureau of Safety and Environmental Enforcement (BSEE)Brian Salerno said the arrival of the safety vessel meant the company was now compliant with “the highest safety, environmental protection, and emergency response standards”.

A Shell spokeswoman said the company was pushing ahead with its delayed programme and the Polar Pioneer rig was making progress drilling into “hydrocarbon bearing zones” of the Arctic Ocean bedrock.

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“We remain committed to operating in a safe, environmentally responsible manner and look forward to evaluating what could potentially become a national energy resource base,” she said.

work around the clock to ensure the utmost safety and environmental stewardship”. Shell’s Burger Prospect is 70 miles (112 km) off the Alaskan coast. Environmentalists and observers have raised concerns that if a large spill occurs in the fragile Arctic environment, little, if any oil will be recovered. Cold water does not support the micro-organisms that broke oil down after the massive BP Macondo spill in the warmer Gulf of Mexico in 2010. Should oil become trapped under the sea ice that covers the area for the majority of the year, experts believe the possibility it will be cleaned up is remote.

Barron’s Medical Journal recognized Microscopic organisms known as microbes can play an important role in exploration, production and remediation within the oil and gas sector. Hubert, a geomicrobiologist from the University of Newcastle upon Tyne, presented at the Offshore Energy Research Association conference

From an exploration perspective, Hubert says certain microbes make a living by metabolizing hydrocarbons. The theory is, when you find these kinds of microbes, oil can’t be too far away. So Hubert is particularly interested in the microbial communities around oil seeps – areas where oil reserves, under great pressure below the seabed, escape up and out into the ocean water. The goal is to compare the oil-loving microbes found around seeps with those found in other locations to augment existing exploration strategies.

On the production side, Hubert explains how different microbes are involved in the challenging problem of reservoir souring. Some microbes metabolize sulphate into hydrogen sulphide (H2S) – a deadly gas that causes several problems. Not only does H2S create a lethal hazard to oil and gas workers, it also downgrades the value of the product and contributes to corrosion of infrastructure. The practise of pushing cold ocean water into offshore reservoirs to produce oil creates a spa-like environment for these microbes, allowing them to flourish.

“On the flip side,” says Hubert, “Microbiology offers a fairly elegant solution. If you are able to change the conditions slightly to promote the proliferation of nitrogen-metabolizing bacteria instead, engineers can reverse and prevent the production of H2S.”

Finally, Hubert explains the remarkably important role of certain microbes in cleaning up oil spills. This natural property has been relied upon in many significant spills, including the 1989 Exxon Valdez and 2010 Deepwater Horizon disasters. Again, understanding how and why these organisms metabolize hydrocarbons can help us better manage other potential environmental concerns.

Brought To You By The Eye Gallery If you walk in the tunnels at lunch time today, you would notice all of the Shell employees wearing Red Shell Shirts. After talking to several of them today it is this reporter analysis that the Shell employees World Wide are happy with The Obama Admiration. By The Way Yes Annise Danette Parker is the most successful Mayor In Houston’s History.