Thursday, December 26, 2013

Affordable Care Act Is A Win: Ninety Four Percent Of People With Pancreatic Cancer Will Have Insurance


Barron’s Medical Journal Robert Graham Ph.D. Reporting from GeorgeTown University Washington, DC USA.

Affordable Care Act Is A Win: Ninety Four Percent Of People With Pancreatic Cancer Will Have Insurance


Washington DC ( AP ) Barron’s Medical Journal has discovered that In Houston Texas we have one of the best Researchers in the World to work with pancreatic cancer. Yes The Baylor College of Medicine Kim Worley, Ph.D.

Number of New Cases and Deaths per 100,000: The number of new cases of pancreas cancer was 12.2 per 100,000 men and women per year. The number of deaths was 10.9 per 100,000 men and women per year. These rates are age-adjusted and based on 2006-2010 cases and deaths.

For several decades, the incidence of pancreatic cancer has been 50% to 90% higher among blacks than among whites in the United States

Lifetime Risk: Lifetime risk is the probability of developing or dying from a disease in the course of one's lifespan. Based on the most recent data, approximately 1.5 percent of men and women will be diagnosed with pancreas cancer at some point during their lifetime.

Prevalence of this cancer: There are an estimated 41,609 people currently living with pancreas cancer in the United States

Kim’s Work with Sea urchin genome is showing advances in the medical and science communities. President Obama now enrolling millions of patients and sixteen percent of Black Men is going to experience pancreatic cancer. We want to put a light on where treatment options can produce the best success. Kim and BCM-HGSC uses genomic and mouse models to work with Sea urchin genome and their research has sequenced chromosomes 6 and 10 of the laboratory mouse (Mus musculus).


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The genome sequence of the mouse was produced by the Mouse Genome Sequencing Consortium. BCM-HGSC finished 178Mb of redundant sequence or ~120 Mb of unique sequence for the mouse project that was completed in December 2005. Barron’s Medical Journal Also wants to high light Dr. Rose Conrad Ph.D. of Sam Houston Biotech. Conrads researchers can compare normal and tumor DNA has shown that the gene for a subunit of the multi-subunit SWI/SNF protein complex was either deleted, mutated or rearranged in about a third of the 70 human pancreatic cancers from the region that the Sam Houston team examined. Sam Houston researchers found that restoring the expression of one of the missing genes slowed the growth of pancreatic cancer cells. The pancreatic cancer enter a state called senescence. "This is really strong genetic evidence that this complex plays a role in pancreatic cancer, and it suggests the influence of the SWI/SNF complex is on par with that of other well-known tumor suppressors, such as p53. The tumor-suppressing role of the SWI/SNF complex We should not that, one person's pancreatic cancer might have a mutation or deletion in one protein subunit, while another's could have a change in a different subunit. Sam Houston used a array comparative genomic hybridization, or CGH, to pinpoint places in the genome that differed among normal and cancerous pancreatic epithelial cells. The procedure relies on the ability of single-stranded DNA to seek out and bind to its mirror image. By comparing the relative amounts of tumor and normal DNA that bind to a panel of reference sequences, the researchers can tell whether the cancer cell contains amplifications or deletions of genetic material in specific regions throughout the genome. These copy-number variations often occur in genes or regions important in regulating uncontrolled cell growth. The researchers examined about 35 different pancreatic cancers, . 24 of the cancers were primary samples from human patients that had been asked to grow in immune-deficient mice; 11 had been maintained as laboratory-grown cancer cell lines. Sam Houston used high-density arrays of reference DNA sequences for the CGH, which allowed the identifi mplified or deleted regions at a much higher resolution than previously possible -- narrowing the areas of interest to just a few

Thousand nucleotides rather than larger stretches of DNA. Sam Houston looked at the results of the array CGH analysis, and observed that genes known to be involved in pancreatic cancer, and also some new candidates. In particular, they noticed that the genes for individual subunits of the SWI/SNF complex were altered in about 5 to 10 percent of the cancer samples -- an interesting finding, but not prevalent enough to spark further immediate investigation under normal circumstances. realized that more than a third of the cancer samples contained a deletion, mutation or rearrangement in the genes.

There are still things to be fixed, for an example many people that earn between $5 and $15 an hour, do not own or use computers and are more comfortable speaking Spanish than English. Sixty-five percent of East Palo Alto’s population is Latino, a group seen as crucial to the success of the health law. Many lack health insurance and pose a lower financial risk because they are typically younger and healthier than others. Yet California, with the greatest number of Latinos in the country, is far behind in reaching this population. And across the nation, the picture appears even worse.

Those who primarily speak Spanish are largely being left out of the first wave of coverage under Obamacare. Many missed this week’s deadline for enrollment in plans beginning Jan. 1. People who want to be covered for any part of 2014 must sign up by March 31.

The Obama administration said Tuesday that it would provide more time for people to complete their applications for health insurance if they could show that they missed the deadline because of problems with the federal health care website.

The deadline has been extended by a day for those who want to receive health insurance coverage through the federal exchange beginning Jan. 1, 2014.

Families with relatives with pancreatic cancer can rest and be assured that help is on the way.

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