Barron’s Medical Journal ---- B.Bobby Graham Reporting : ---- From Surpreme Court Washington DC -- USA < GlobeNewswire>< PRWire> < PRNewswire>
Same Sex Marriage -Changing Thousands Years Of Thinking In Only Ten Years :
Washington DC -- BMJPress -- The United States Supreme Court Is making a decision on Same Sex Marriage. The question is should we change 
thousands years of thinking after only considering about ten years of courts cases. At Barron Medical Journal we decided to look under the hood on this issue and investigate the science behind this matter. Barron’s research shows scientist have identified gene’s associated with being gay in males.
Some background on human genes and its DNA associations. A gene is a physical structure made from DNA. Genes function primarily by being expressed in the form of proteins. The conversion from gene to protein is a multistage process. First the gene is transcribed, making a RNA copy of itself that is then translated to create a protein.
At least in men, homosexuality may be a function of genetics, according to a study of more than 400 pairs of gay brothers. The research, published in 
Psychological Medicine, confirms the role of a stretch of the X chromosome in determining sexual preference in men, a finding first suggested more than 20 years ago.
The Supreme Court is giving indications to voting on this matter down party lines. The one Justice all stake holders are paying special attention to is Justice Kennedy. Justice Kennedy. He said he was concerned about changing a conception of marriage that has persisted for thousands of years based on little more than a decade of experience with same-sex marriage in the United States.
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“I don’t even know how to count the decimals when we talk about millennia,” he said. “This definition has been with us for millennia. And it’s very difficult for the court to say, ‘Oh, well, we know better.’ ” He added that “the social science on this” — the value and perils of same-sex marriage — is “too new.”
Later, though, he expressed qualms about excluding
gay couples from the institution of marriage.
“Same-sex couples say, of course: ‘We understand the nobility and the sacredness of the marriage. We know we can’t procreate but we want the other attributes of it in order to show that we, too, have a dignity that can be fulfilled,’ ” Justice Kennedy said, strongly suggesting that the reasoning resonated with him.
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One of the leading scientist on the question of can our genes decided if we are gay or not is Dean Hamer. Dean is an American geneticist, author, and filmmaker. He is known for his contributions to biotechnology and AIDS prevention, his research on the genetics of human behavior. Dean 
study in 1993 proposed , Xq28, a region of the X chromosome, might play a role in determining whether a man was gay.
The X chromosome (Xq28) in sexual orientation by DNA linkage analyses of two newly ascertained series of families that contained either two gay brothers or two lesbian sisters as well as heterosexual siblings. Linkage between the Xq28 markers and sexual orientation was detected for the gay male families but not for the lesbian families or for families that failed to meet defined inclusion criteria for the study of sex−linked sexual orientation. Our results corroborate the previously reported linkage between Xq28 and male homosexuality in selected kinships and suggest that this region contains a locus that influences individual variations in sexual orientation in men but not in women.
Duplications in the telomeric neighboring regions, which include GDP dissociation inhibitor 1 gene (GDI1) and ras-associated protein RAB39B gene (RAB39B), are independently associated with ID, and many segmental duplications located in this region could mediate these frequently observed interstitial duplications.
The only question now is there going to be a company in the United States to lead in building tools to find answers to question such as, is there a gene or genes 
associated with being a gay male. One organization we found to be performing creditable research in this area is the The German cDNA Consortium.
Stefan Wiemann (DKFZ), H. Blöcker (GBF Braunschweig); A. Bahr (Qiagen GmbH Hilden); K. Köhrer (BMFZ Düsseldorf); W. Ansorge (EMBL Heidelberg); H.W. Mewes (GSF München); B. Ottenwälder (Medigenomix GmbH München); D. Heubner (AGOWA GmbH Berlin)
The German cDNA Consortium (see below) was formed in 1996 as the world's second large-scale cDNA analysis project, and aimed at systematically generating (Wellenreuther 2004), sequencing and annotating full-length cDNAs of human genes. The resources produced in this project have been our contribution to the ORFeome Collaboration and have substantially helped to reach comprehensive coverage of the human genes in that resource.
While gene identification was initially through EST-sequencing of cDNA libraries (we generated ESTs from ~250,000 cDNAs, and completely sequenced 15,000 full-length cDNAs), we later shifted towards the directed modelling of gene structures and the cloning of respective ORFs. The project was part of the National Genome Research Network (NGFN). We have adapted and routinely apply the Gateway cloning system (Invitrogen) for the cloning of protein coding regions (ORFs) (Simpson 2000, Bechtel 2007). This system is based on recombination and allows for the base specific and directional cloning of DNA. With a high level of automation we amplify the ORFs in a 2-step PCR process, adding 5' and 3' flanking Gateway compatible sites. Universal `entry clones´ are generated via recombination, they are compatible with any Gateway expression vector. The entry
clones are completely sequence verified as an important step in the quality control process. Inserts of verified entry clones are recombined into a range of expression vectors. These constructs are utilised in functional profiling to determine the sub-cellular localisation of encoded proteins (-> LIFEdb) and to identify cellular effects of protein overexpression in cell-based functional assays (Wiemann 2004, Starkuviene 2004, Arlt 2005, Laketa 2007, Sauermann 2007). Based on these screens, a number of new functions and disease associations could be associated with respective hits (Neubrand 2005, Fleischer 2006, Sauermann 2008). Furthermore, the clone resource has been exploited in a number of collaborative projects (e.g.,Will 2010, Bai 2011, Lisauskas 2012, Simpson 2012, Walde 2012)
The sequence resources and expertise of the German cDNA Consortium have been basis of the systematic functional annotation of the human transcriptome, which has been carried out by the international H-invitational consortium (Imanishi 2004, Yamasaki 2008). The complete annotation is publicly available in the H-invitational database (http://www.h-invitational.jp/).
The winner in this area of clinical research is Genomics Science. Just a taught when you are choosing a major.
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