Monday, March 18, 2013

Science Is Going To Be More Profitable Than Oil And Gas With (B.A.M) Brain Activity Mapping


Barron's Medical Journal Reporting From The United States Congress Capitol Hill, Washington DC, USA
Science Is Going To Be More Profitable Than Oil And Gas With (B.A.M) Brain Activity Mapping

Washington, DC ( AP )Barron's Medical Journal in Washington DC getting ready for the announcement from President Obama Administration to ask Congress for funding to map the human brain. B.A.M Brain Activity Mapping will do for Neuroscience what the Human Genome Project has done for genetics. For every dollar The Federal Government has invested in the Human Genome Project, The American People has received a return on investment of Two Hundred and Forty Dollars.

Our brain is vast on a cosmic scale. Billions upon billions of neurons communicate with one another via trillions of connections, giving rise to what amounts to a network of networks. Widely adopted (but by no means universally accepted) theories posit that these neural networks are the wellsprings of such complex processes as perception and action.Neuro Scientists believe that a detailed BAM Brain Activity Mapping reveals valuable information about these and other cognitive functions, and perhaps human consciousness.

The Obama Administration has sought in planning a ten-year, multi-billion dollarproject. Everything that we are, our whole mental world, amounts to nothing more than neural circuits firing [in patterns] throughout the brain. By mapping circuit activity, researchers can "discover patterns that are the physical representation and origin of mental states — of thoughts, for example, or memories."

There are one million gigabytes in a petabyte. The Large Hadron Collider in Geneva generates about 10 petabytes of data annually. If the brain contains between 85 and 100 billion neurons, that means that the complete brain generates about 300,000 petabytes of data each year.

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A "static" model — a wiring diagram that charts how neurons connect with one another. A "functional" model, can go much further, by allowing researchers to see not just the connections between the tens of billions of neurons that comprise a human brain, but the individual action of every cell in a given neural circuit. George Church, a molecular geneticist at Harvard University,says the difference between knowing the spatial distribution of a city's telephone wires and knowing where, when, and how those wires are transmitting messages. (An early architect and longtime ambassador of the Human Genome Project, Church has been tapped to work on the BAM project, and is a co-author on last year's white paper.)

A technological revolution in the field of neuroscience. It is currently possible to insert electrodes into the brain that can both monitor and induce brain activity. But the resolution offered by these and less invasive techniques is poor. That means the first step toward a BAM will be to develop tools that can actually record the individual activity of every neuron in a brain circuit. The second step will be to create tools that can influence the activity of individual neurons.

BAM "is essentially a technical development project," aimed at devising techniques that can both measure and stimulate neurons with exquisite spacial specificity. Development and implementation of these tools would, of course, begin on smaller organisms and mice. Specific brain regions, progressing toward the ultimate goal of plotting the real-time activity of the neurons and networks in an entire human brain. "every single tool or technique [developed] will be immediately be released for the entire neuroscience community."

Launching the Human Genome Project and conducting it in a centralized fashion was that researchers were already searching for disease genes and sequencing the genome in piecemeal. It was going to get done one way or the other, but it was going to happen in thousands of little bits at a time — highly inefficient from the standpoint of time and money. Centralizing the process through the Human Genome Project dramatically reduced costs while accelerating the mapping process toward a certain goal with definitive applications.

The potential for financial return will be more economically powerful than Human Genome Project. We learned from the HGP experience that technology should be done as early as possible," says Church, noting that he price of genome sequencing may have been brought down a million-fold, but only after the HGP project was over. "If you mix technology development and applications from the beginning, I think you wind up with a more cost effective, and relevant project. Those are things that we're going to do differently this time around." "Humans are nothing but our brains.The potential applications for technology produced in pursuit of a map of human brain activity. "Our whole culture, our personality, our minds, are a result of activity in the brain. New medical technologies like brain-computer interfaces for cochlear, epilepsy, spinal injury and retinal implants. These devices will improve, and at an enormous benefit to the economy.

It is clear to Barron's Medical Journal we are not going to connect Genomics with Brain Activity Mapping and open up the door for young STEM Students to have promising careers for years to come. Brain Activity Mapping is the next thing in science Says Sam Houston Biotech Center.

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