Friday, October 31, 2014

Houston Science Community Solves The Ebola Puzzle


Houston Science Community Solves The Ebola Puzzle Barron's Medical Medical Journal Reporting From Rice University Houston, Texas USA

Houston ( AP) Houston Science Community has the goods to solve the Ebola puzzle. Barron’s Medical Journal has discovered the research conducted by Houston Methodist Research Institute. Dr. James Musser is using genomic science and mice models to find a cure for embola. It turns out not all Americans will react to exposure to the embola virus the same way. This is a amazing find. To discover the Gene TIE1 has moved the ball down the field for a complete cure.

----TIE1 is a cell surface protein expressed exclusively in endothelial cells, however it has also been shown to be expressed in immature hematopoietic cells[2] and platelets.[3] TIE1 upregulates the cell adhesion molecules (CAMs)VCAM-1, E-selectin, and ICAM-1 through a p38-dependent mechanism. Attachment of monocyte derived immune cells to endothelial cells is also enhanced by TIE1 expression. TIE1 has a proinflammatory effect and may play a role in the endothelial inflammatory diseases such as atherosclerosi.

Dr. James Musser, director of the Center for Molecular and Translational Human Infectious Diseases Research at Houston Methodist Research Institute. Using mice in experiments, he said, can change the nature of Ebola research. Until now, investigators have mostly used macaques, guinea pigs, and Syrian hamsters because the mouse strain they usually study does not get an Ebola infection that mimics how human patients react.

“This provides a tremendous opportunity to drive toward answers to questions that heretofore were intractable,” Dr. Musser said, mentioning in particular the question of how much genetics determines susceptibility or resistance to Ebola. He added that the mice could be invaluable in initial tests of vaccines and potential drugs. Dr. Matthew Waldor, an infectious disease researcher at Brigham and Women’s Hospital who also was not involved with the study, had the same opinion, calling it “a cool study.” The work, by Angela L. Rasmussen and Michael G. Katze of the University of Washington and their colleagues, began three years ago, long before the current Ebola epidemic. They were inspired by their studies with the 1918 influenza virus that caused a worldwide lethal pandemic. Using a variety of mouse strains, they found that genetics determined whether a mouse got sick or died from the flu, or never got sick at all. People, too, seem to have different responses to the same influenza virus. Dr. Katze, who has studied Ebola for the past decade, and Dr. Rasmussen, who chose to study infectious diseases because when she was in college she read “The Hot Zone,” a book that told a terrifying tale of Ebola in Africa, wanted to find out if genes determine responses to Ebola.

The better News is that Genomics is on the Clock. Genomics provide a faster cheaper more effective way to detect the TIE1 gene by using Semiconductor Sequencing. A example of this technique is Hybrid Pharmaceuticals. Gennxeix Semiconductor Sequencing. “Quantum Theory” In Action for Ebola Patients. A polymerase is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA. The primary function of a polymerase is the polymerization of new DNA or RNA against an existing DNA or RNA template in the processes of replication and transcription. In association with a Hybrid Pharma , Gennxeix also uses a Visualize Real-Time Ebola Data using Signal Stochastic Resonance Units Neurons Detection and Analysis for Ebola model after McCulloch-Pitts.

Hybrid Pharmaceuticals computer-assisted diagnosing of Ebola. Hybrid Pharmaceuticals works is a genetic network simulation trained with tumor incidence data from knockout experiments. Gennxeix Biotech uses Semiconductor Sequencing Chips that create a direct connection between Biochemical and digital information, bringing these two languages together. Hybrid’s chips are designed like any other semiconductor chips. Pairing proprietary semiconductor technology with sequencing chemistry a nucleotide is incorporated into a strand of DNA by a polymerase, a hydrogen ion is released. Gennxeix Biotech used a high-density array of micro-machined wells for bioctechnology process in a massive way. Each well holds a different DNA template. Beneath the wells is an ion-sensitive layer and beneath that a proprietary Ion sensor. TIE1 in many patients respond differently. Genomics can be the GPS to Extend life in Ebola Patients. formalin fixed, paraffin embedded techniques and TIE1 Approximately Where do you really come from? And how can this information Solve Breast Cancer? Approximately 30% of malignant breast cancers demonstrate overamplification of the human epidermal receptor type 2 (HER2) gene. TIE1 can be resistant to low-doses of anthracycline-based Hybrid Pharma have demonstrated that they can be used to map DNase (deoxyribonuclease) DNA origins of replication. Hybrid Pharma Recent progress in microarray technology has been related to the development of high resolution microarrays which can map genomic alterations and constitutional variants in DNA copy number at an extremely high resolution for Ebola chemotherapy. formalin fixed, paraffin embedded techniques.

The Good News is that science has advanced. Sections of microarray provide targets for parallel in situ detection of DNA, RNA and protein targets in each specimen on the array. The better News is that Genomics is on the Clock. Genomics provide a faster cheaper more effective way to detect the TIE1 gene by using Semiconductor Sequencing. A example of this technique is Hybrid Pharma Semiconductor Sequencing. “Quantum Theory”, In Action for Ebola Patients. A polymerase is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA. The primary function of a polymerase is the polymerization of new DNA or RNA against an existing DNA RNA template in the processes of replication and transcription. In association with a Hybrid Pharma also uses a Visualize Real-Time Ebola Data using Signal Stochastic Resonance Units Neurons Detection and Analysis for Ebola model after McCulloch-Pitts. Hybrid Pharma computer-assisted diagnosing of Ebola from mammograms. Hybrid Pharma Gennxeix works is a genetic network simulation trained with tumor incidence data from knockout experiments. Gennxeix Biotech uses Semiconductor Sequencing Chips that create a direct connection between Biochemical and digital information, bringing these two languages together. Hybrid’s chips are designed like any other semiconductor chips. Pairing proprietary semiconductor technology with sequencing chemistry a nucleotide is incorporated into a strand of DNA by a polymerase, a hydrogen ion is released.

Gennxeix Biotech used a high-density array of micro-machined wells for bioctechnology process in a massive way. Each well holds a different DNA template. Beneath the wells is an ion-sensitive layer and beneath that a proprietary Ion sensor. The TIE1 genes in many patients response differently. Genomics is the GPS to Extend life in Ebola Patients

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